Abstract Book - 26th ESPU Congress, Joint Meeting with ICCS + SPU + AAP/SOU + AAPU + SFU

S14-19

(P)

ANALYSIS OF PREOPERATIVE ANTIBIOTIC THERAPY IN STENTED, DISTAL

HYPOSPADIAS REPAIR

Stephen CANON

, Jacob SMITH

, Ashay PATEL

, Ismeal ZAMILPA

and Jeffrey ALLISTON

1) Arkansas Children's Hospital, Pediatric Urology, Little Rock, USA - 2) University of Arkansas for Medical Sciences,

Pediatric Urology, Little Rock, USA - 3) University of Texas Health Science Center at Houston, College of Medicine,

Houston, USA

PURPOSE

Even though preoperative antibiotics have not been shown to effectively reduce surgical site infections (SSIs) for

stented, distal hypospadias repair, 77% of pediatric urologists use antibiotics in this setting (Hsieh et al. JPU 2011; 7.2:

192-197). In light of variation in use of preoperative antibiotics at our institution, we sought to determine whether

preoperative antibiotic utilization impacted the prevalence of SSI.

MATERIAL AND METHODS

We retrospectively reviewed all boys treated with stented, distal hypospadias repair from 2011-2014. Consecutive

patients with primary distal penile, subcoronal, coronal, and glanular hypospadias repair using urethral stent drainage

were included with all hypospadias revisions excluded. Variables included were utilization of preoperative antibiotic

therapy (Cefazolin) and presence of SSI (defined by the presence of postoperative penile erythema and/or purulence

treated with therapeutic antibiotics). The two cohorts were compared using the Fisher exact test.

RESULTS

We queried the clinical hypospadias database at our institution with 229 consecutive patients identified in these 2

groups: 138 patients treated with preoperative antibiotics and 91 patients treated without preoperative antibiotics.

While no patients in the preoperative antibiotic therapy group were found to have SSI, one patient treated without

preoperative antibiotic therapy was found to have an SSI (p-value of testing association = 0.4).

CONCLUSIONS

The overall incidence of surgical site infections in patients treated with stented, distal hypospadias repair observed was

very low. We observed no difference in the rate of surgical site infections for the two groups treated with or without

preoperative antibiotic therapy. Further prospective study with randomization is recommended.