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S21-11

(P)

PAEDIATRIC SACRAL NERVE STIMULATION; THE SOUTHAMPTON EXPERIENCE.

Judith DOCKRAY, Kerry WILKINSON and Henrik STEINBRECHER

University Hospitals Southampton, Paediatric Urology, Southampton, UNITED KINGDOM

PURPOSE

Sacral Nerve Stimulation (SNS) is an established modality for the treatment of lower urinary tract symptoms in adults,

particularly related to overactive bladder (OAB). Its use in children is being slowly established, though evidence is

largely based around single-centre experiential studies on children with mixed urinary and faecal symptoms.

MATERIAL AND METHODS

We present our 4 year, prospectively collected, experience of the SNS use, for a series of 9 children aged 7-15 with

urodynamically proven detrusor overactivity. 7/9 of the group were female and 2/9 male. 7/9 patients had a diagnosis

of idiopathic detrusor overactivity and 2/9 had neuropathic detrusor overactivity. All patients had failed medical

treatment with at least 2 anticholinergics and desmopressin. All had tried Transcutaneous Electrical Nerve Stimulation

(TENS) and intravesical botulinum toxin injection as second and third-line treatment.

RESULTS

9 patients had temporary test wires inserted. 6/9 patients experienced a "good" response, classed as significant (≥50%)

improvement of symptoms or complete cure. They went on to permanent box insertion. 2/6 patients required revision

surgery in the form of minor wire adjustments. 1 patient requested removal of her system due to lack of response.

Of the 3/9 who did not respond to the test wire. 1/9 was cured on wire removal, 1/9 progressed to augmentation and

1/9 continued on medical therapy.

CONCLUSIONS

Our data confirms a success rate consistent with the literature available for adult and mixed symptom

paediatric groups. It is one of the larger series specifically looking the application in paediatric urinary

incontinence.

The data is limited by the lack of sensible validated questionnaires, the vast differences in expectations and

issues with compliance that make urinary incontinence such a challenging problem in this age group. The

high success rate, combined with low side-effect and complication profile make this an attractive alternative

before augmentation is considered.