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S21-6
(PP)
THREE MONTHS OF ADEQUATE FLUID INTAKE RESULTS IN THE SAME INCREASE
OF BLADDER CAPACITY AS THREE MONTHS OF ANTIMUSCARINIC THERAPY.
Liesbeth Lilian DE WALL
1
and Goedele Maria Angele BECKERS
2
1) VUmc, Urology, Amsterdam, NETHERLANDS - 2) VU University Medical Centre, Department of Urology, Amsterdam,
NETHERLANDS
PURPOSE
Adequate fluid intake is considered important in the treatment of small bladder capacity (SBC) for age without
knowledge of it's real effect on bladder growth. We hypothesized an equal increase in bladder capacity after three
months of adequate fluid intake as part of nonpharmacological treatment (NPT), compared to adequate fluid intake
combined with antimuscarinic therapy (AMT).
MATERIAL AND METHODS
A retrospective chart analysis of all children presenting with SBC was conducted between October 2004 and June 2013.
Children with congenital or neurological anomalies, previous medical treatment or urinary tract surgery were excluded.
Children receiving NPT were age-matched to children with NPT + AMT. Voiding chart parameters and fluid intake were
recorded at time of diagnosis and after three months of treatment.
RESULTS
67 children were included. NPT was started in 32 children after diagnosis. NPT was combined with AMT (oxybutynin
0,1mg/kg tid) in 35 children. Initial patient demographics, voiding chart parameters and fluid intake were not
significantly different between groups. After three months, bladder capacity and fluid intake significantly increased in
both groups (resp. p <0.001, p=0.001) without a significant difference in increase of bladder capacity between groups
(p=0.600). Bladder capacity increased with an average of 41 cc in the NPT group and 53 cc in the AMT + NPT group.
CONCLUSIONS
After three months of NPT no significant difference was seen in increase of bladder capacity compared to a combination
of NPT and AMT. In our opinion, the role for AMT at start of treatment of SBC can be discussed.