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ACCEPTABILTY AND EFFICACY OF POSTERIOR TIBIAL NERVE STIMULATION IN
PAEDIATRIC OVERACTIVE BLADDER: A PROSPECTIVE STUDY
M S ANSARI
1
, Nitish PATIDAR
2
and Aneesh SRIVASTAVA
2
1) Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Urology and renal transplantation,
Lucknow, INDIA - 2) Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, INDIA
PURPOSE
Various methods of neuromodulation have been reported to treat refractory lower urinary tract dysfunction. Most of
these techniques are invasive, hence less applicable in children. We evaluated the effectiveness of transcutaneous
posterior tibial nerve stimulation (PTNS) to treat overactive bladder (OAB) in children. We designed a prospective
randomized trial with sham control for this evaluation.
MATERIAL AND METHODS
All the children enrolled easily accepted the PTNS in both the groups. This study was single-blinded, prospective, sham
controlled randomized trial. 40 children with non-neurogenic OAB refractory to behavioural and anticholinergic therapy
were randomized either to test group or sham group. A total of 12 sessions, 30 minutes each were performed weekly.
The OAB symptoms, severity of incontinence, number of voids daily (NV), average voided volume (AVV) and maximum
voided volume (MVV) were evaluated before and after the treatment. Statistical analysis was done using SPSS version
22.0.
RESULTS
On assessment of subjective improvement of OAB symptoms, 66.66% patients reported cure and 23.81% patients
reported significant improvement of symptoms in test group whereas in sham group only 6.25% patients reported
significant improvement. In test group 71.42% patients reported complete improvement in incontinence and 23.81%
patients reported mild incontinence only, whereas in sham group only 12.5% patient reported complete improvement.
The AVV, MVV and NV improved significantly in test group (p <0.001) as compared to sham group.
CONCLUSIONS
Transcutaneous PTNS is easily acceptable and highly effective in children with OAB refractory to behavioral and
antecholinergic therapy.