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ENTEROCYSTOPLASTY: THE LONG TERM EFFECTS ON BONE MINERAL DENSITY
Terry HENSLE MD,FACS,FAAP
COLUMBIA UNIVERSITY COLLEGE OF P&S, UROLOGY, Haworth, USA
PURPOSE
Studies have shown that bone mineral density is adversely effected by enterocystoplasty. It was our goal to look at the
long term effects of enterocystoplasty on bone mineral density. Using the DEXA scan as a marker for BMD, we
attempted to identify the long term effects of enterocystoplasty. We hoped to identify patients at risk for the
development of both osteopenia and osteoporosis and the potential for long term fracture risk.
MATERIAL AND METHODS
We reviewed our database of enterocystoplasty in children and young adults. We were able to identify 23 individuals
who had undergone these procedures and been followed for more than 15 years.
RESULTS
Using DEXA scan technology, the identification of both osteopenia and osteoporosis were made on the basis of T scores
and Z scores. There were 11 of the 23 patients in our series with normal DEXA scans and normal T and Z scores. There
were 7 individuals with identifiable osteopenia and increased fracture risk. There were 5 individuals classified as having
osteoporosis. Three in this group of 5 individuals also had reduced GFR.
CONCLUSIONS
The loss of BMD can be seen in individuals who have undergone enterocystoplasty during childhood. The loss does not
seem to be related to the long term enterocystoplasty alone. The loss is more pronounced in individuals who have other
risk factors such as reduced GFR. We believe the identification of BMD loss is important in order to intervene before
osteoporosis occurs and leads to pathologic fracture.