304 / 492
S24-6
(P)
TREATMENT REFRACTORINESS OF PRIMARY NONMONOSYMPTOMATIC ENURESIS
IS ASSOICATED WITH SPINA BIFIDA OCCULTA AND RECTAL STOOL IMPACTION
Jung Keun LEE, Tae Sik AHN, Minyong KANG and Kwanjin PARK
College of Medicine, Seoul National University, Urology, Seoul, KOREA (REPUBLIC OF)
PURPOSE
To evaluate the effects of the spina bifida occulta (SBO) and stool length in rectum (SLR) on treatment response in
primary nonmonosymptomatic enuresis (PNME)
MATERIAL AND METHODS
We retrospectively analyzed 151 children with PNME who had been treated by a single pediatric urologist between July
2010 and July 2014. A simple abdominal radiograph was conducted to examine SBO and SLR. The average voided
volume by estimated bladder capacity (AVV/EBC) ratio was calculated using frequency volume chart. Insufficient
response was defined as no response or partial response. The logistic regression analysis was used to clarify a
significant parameter for affecting insufficient response. Cumulative response rate was analyzed using Kaplan-Meier
curve.
RESULTS
Mean age of children was 6.9 years. Of these patients, SBO was detected in 28.5%. A mean SLR was 6.8cm, and a
mean AVV was 107 ml. During a mean follow-up of 12.5 months, insufficient response had occurred 63.3% at 6 months
and 39.8% at 12 months. In the logistic regression analysis, SBO (OR 2.78, p=0.025) and SLR ≥8cm (OR 4.62,
p=0.008) were only significant parameters for affecting insufficient response in 6 months. The SBO (OR 6.71, p<0.01),
SLR ≥8cm (OR 7.97, p<0.01), and AVV/EBC ratio ≤0.25 had significant correlation with insufficient response in 12
months. In Kaplan-Meier curve, a risk group consist of SBO or SLR≥8cm had worse response rate than another
(p=0.008).
CONCLUSIONS
The results highlight clinical importance of SBO and SLR for predicting treatment refractoriness. These parameters would
be applied for stratification of children with PNME.