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ESPUN S3: NEUROPATHIC BLADDER

Moderators: Louiza Dale (UK) & Hanny Cobussen (Netherlands)

ESPU-Nurses Meeting on Thursday 15, October 2015, 09:00 - 09:35

09:00 - 09:10

ESPUN S3-1

(O)

CAN 4-HOUR VOIDING OBSERVATION DETECT NEUROGENIC BLADDER

DYSFUNCTION IN NEONATES WITH ANORECTAL MALFORMATION?

Helena BORG, Charlotte ARWIDSSON, Gundela HOLMDAHL and Ulla SILLÉN

Queen Silvia Children's hospital, Department of Pediatric surgery, Gothenburg, SWEDEN

PURPOSE

Neurogenic bladder dysfunction (NBD) is present in about 25% of patients with anorectal malformation (ARM). The aim

was to determine if non-invasive investigation of bladder function with 4-hour voiding observation (FVO) can replace

cystometry in diagnosing NBD.

MATERIAL AND METHODS

FVO was performed in 34 patients pre- and post anorectal surgery (median age 4 and 14 months respectively),

including registration of voiding pattern, number of voiding(≤8), leakage, bladder capacity(≥50% of expected) and

mean residual (ultrasound, ≤10ml). For diagnosis of NBD, cystometry was performed. Bladder function was also

followed longitudinally with a structured questionnaire and flow-residual measurements.

RESULTS

All patients with cystometric diagnosed NBD (n=9) or non-neurogenic neurogenic dysfunction (n=1) presented abnormal

voiding variables. Mild abnormalities were registered in 3 girls with tethered cord: Voiding frequency (10-13) and

residual (mean 10-14 ml) were increased and bladder capacity <50%. A pathologic voiding pattern was seen in 5 boys

with spinal cord malformation: Urinary leakage, small voided volumes, frequent voiding (13-22) and incomplete

emptying. High bladder capacity and large residual were recognized in the remaining two patients.

The majority of patients, without known NBD or severe functional disturbance (n=24), had normal voiding pattern. A

moderate increase in residual was seen in 5 patients and with high bladder capacity in two. These 5 patients had periods

with bladder dysfunction during follow-up.

CONCLUSIONS

4-hour voiding observation can detect NBD in patients with ARM, especially severe dysfunction, and can therefore be

used for screening of NBD. However, it cannot replace cystometry in follow-up of patients with NBD.