Abstract Book - 26th ESPU Congress, Joint Meeting with ICCS + SPU + AAP/SOU + AAPU + SFU

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ICCS S3-10 (P)
DDAVP THERAPY AND ALARM THERAPY FOR NOCTURNAL POLYURIA
Yasuyuki NAITOH1, Yasuhiro YAMADA 1, Atsuko FUJIHARA1, Koji OKIHARA1, Kazuyoshi JOHNIN2 and Akihiro KAWAUCHI2
1) Kyoto Prefectural University of Medecine, Urology, Kyoto, JAPAN - 2) Shiga University of Medical Science, Urology,
Otsu, JAPAN
PURPOSE
We investigated treatment outcomes of DDAVP therapy and alarm therapy performed in patients with nocturnal polyuria
who visited our department.
MATERIAL AND METHODS
Of patients with monosymptomatic nocturnal enuresis who visited our department, 24 nocturnal polyuria patients with
normal diurnal bladder capacity and above 130% of the bladder capacity expected from their ages were included in this
study. DDAVP therapy was performed in 50 subjects between 7 to 14 years old (mean age: 9.9 years old). Of these, 13
subjects (26%) had nocturnal polyuria. Alarm therapy was performed in 50 subjects between 7 to 14 years old (mean
age: 10.0 years old). Of these, 11 subjects (22%) had nocturnal polyuria. Control were defined as children without
nocturnal polyuria whose bladder capacity was within the normal.
RESULTS
Treatment outcomes of DDAVP therapy performed in subjects with nocturnal polyuria (13 subjects) were as follows: at 3
months after the start of treatment, partial response: 3 (23%); response: 3 (23%); and at 6 months after the start of
treatment, partial response: 3 (23%); response: 3 (23%). Treatment outcomes of control subjects were as follows: at 3
months, partial response: 14 (38%); response: 7 (19%); and at 6 months, partial response: 16 (43%); response: 7
(19%). Treatment outcomes of alarm therapy performed in subjects with nocturnal polyuria were as follows: at 3
months, partial response: 4 (36%); response: 0 (0%); and at 6 months, partial response: 6 (55%); response: 0 (0%).
Treatment outcomes of control subjects were as follows: at 3 months, partial response: 18 (46%); response: 0 (0%);
and at 6 months, partial response: 18 (46%); response: 4 (10%).
CONCLUSIONS
There are definitely not a large number of patients who meet the criteria for nocturnal polyuria according to the ICCS
Guidelines. No significant difference was observed in treatment outcomes between DDAVP therapy and alarm therapy
performed in patients who met the criteria for nocturnal polyuria.