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S4-19

(P)

DO THE TYPE OF BULKING AGENTS AND INJECTION METHOD HAVE ANY

INFLUENCE ON THE INCIDENCE OF URETERAL OBSTRUCTION BY ENDOSCOPIC

TREATMENT OF REFLUX?

Rashit BAYBIKOV

1

, Vladimir SIZONOV

2

, Sergey BONDARENKO

3

, Boris DOLGOV

4

, Vitali DUBROV

5

, Ilia KAGANTSOV

6

,

Alexandr PIROGOV

7

, Vadim SHKLYAR

2

and Dmitry SCEDROV

2

1) Children's Republican Clinical Hospital, Paediatric Urology, Kazan, RUSSIAN FEDERATION - 2) Regional Children's

Hospital, Paediatric Urology, Rostov On Don, RUSSIAN FEDERATION - 3) Regional Hospital 7, Paediatric Urology,

Volgograd, RUSSIAN FEDERATION - 4) Hospital im.S.R.Mirotvortseva, Paediatric Urology, Saratov, RUSSIAN

FEDERATION - 5) 2nd CHILDREN'S HOSPITAL, Paediatric Urology, Minsk, BELARUS - 6) Republic Children's Hospital,

Paeditric Urology, Syktyvkar, RUSSIAN FEDERATION - 7) Regional Children's Hospital, Paeditric Urology, Astrakhan,

RUSSIAN FEDERATION

PURPOSE

To research the effect of the type of bulking agents and injection method on the frequency of ureteral obstruction (UO).

MATERIAL AND METHODS

During 1998-2014, endoscopic treatment in 3782 patients (4898 ureter) was performed in 9 clinics in Russia and

Belarus. I group - 2134 ureters, polyacrylamide copolymer was used, II group in 1424 ureters collagen was used, III

group - 762 ureters, polyacrylate polyalchohol copolymer was used and group IV -578 ureters, dextranomer / hyaluronic

acid was used. The method STING was used in 3984 ureters (81.3%) and HIT in 914 ureters (18.7%). The patients

were followed up by ultrasonography the next day after injection, in a month and every 3 months during the year. For

statistical analysis binary logistic regression was used.

RESULTS

High probability of formation of UO was statistically more significant (p = 0.0001) in patients of groups III (14) and IV

(8) in comparison with children of groups I (9) and II (2). Not statistically significant differences were found in the

frequency of UO in comparison with patients of groups III and IV (p = 0.5). UO was reported in 18 (0.45%) patients

after the injection performed by STING, which was significantly less (p <0.0001), than when we used the HIT method-

15 (1.6%).

CONCLUSIONS

The risk of ureteral obstruction using polyacrylate polyalchogol copolymer and dextranomer/hyaluronic acid was higher

than using collagen and polyacrylamide copolymer. The use of HIT increases the risk of obstruction.