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16:27 - 16:30

S11-6

(PP)

ELEVEN YEAR PIONEER EXPERIENCE ON LAPAROSCOPIC NEPHRECTOMY FOR

TREATMENT OF WILMS TUMOR: BRAZILIAN PIONEER EXPERIENCE IN A SINGLE

INSTITUTION.

Ricardo DUARTE

1

, Lilian CRISTOFANI

2

, Francisco DENES

1

, Vicente ODONE-FILHO

2

and Miguel SROUGI

1

1) University of Sao Paulo, Urology, Sao Paulo, BRAZIL - 2) University of Sao Paulo, Pediatric Oncology, Sao Paulo,

BRAZIL

PURPOSE

The aim of this study was to report a 11 year retrospective analysis of the results on the videolaparoscopic

nephrectomy for the treatment of Wilms tumor, regarding surgical results, immediate and long term complications and

survival.

MATERIAL AND METHODS

From December 2003 to December 2014 23 children with unilateral Wilms tumor were treated with preoperative

chemotherapy followed by videolaparoscopic nephrectomy. The analysis included complications, transfusion, ruptures,

margins, conversions, lymph nodes, and relapse. Kaplan-Meyer method was used for survival analysis.

RESULTS

23 children were submitted to videolaparoscopic nephrectomy. Mean surgical time was 170.71±26.07 minutes and there

were no conversions or ruptures. Mean specimen weight was 142.02±105.85 (range 80 – 515 g) . No transfusions were

required. Surgical margins were positive in 1/17 cases (5.9%). Ten children were stage I, six stage II, 3 stage III and

four stage IV. One patient had focal anaplasia. 2/23(8.6%) patients presented tumor relapse: 1 local (positive margins

and) and 1 in lungs. The 10-year-event-free-survival was 91.3% (0.95 CI: 0.704-0.984).

CONCLUSIONS

Videolaparoscopic nephrectomy after preoperative chemotherapy for the treatment of children with Wilms tumor is safe

and promotes the same long term survival results as open approach.