Abstract Book - 26th ESPU Congress, Joint Meeting with ICCS + SPU + AAP/SOU + AAPU + SFU

14:28 - 14:32

ICCS S1-6

(SO)

CAN CHILDREN WITH OVERACTIVE BLADDER (OAB) AND DYSFUNCTIONAL

VOIDING (DV) TRANSITION BETWEEN EACH OTHER? (IE, ARE THEY ONE

DISEASE?)

Kenneth GLASSBERG

, Jason VAN BATAVIA

and Andrew COMBS

1) Columbia University Medical Center, New York-Presbyterian Hospital, Urology, New York, USA - 2) Weill Cornell

Medical College, Cornell University, Urology, New York, USA

PURPOSE

In 1998, the first ICCS terminology document suggested that “urge syndrome”, later replaced by the term “OAB”, and

“DV” can transition into one another. It was our goal to determine if this phenomenon actually occurs. To create an

objective study, objective “qualifiers” to support the diagnosis of each of the 2 conditions were introduced.

MATERIAL AND METHODS

For the diagnosis of DV we included the qualifier of an active EMG during voiding on 2 occasions. For OAB, we used the

qualifiers of a short lag time and quiet EMG during voiding, ie, IDOD.

RESULTS

Mean follow up of 77 children with DV and 77 with OAB was 17.5 months and included 475 uroflow/EMGs. Mean age for

DV was 6.5 years and OAB 7.2 years. Of the 77 OAB children, none transitioned into DV, although 2 demonstrated

transient mild DV on a single study. Of the 77 with DV, 25 of 31(81%) treated with biofeedback alone and only 8 of 39

(21%) treated with biofeedback and anticholinergics had a short lag time on at least one occasion during follow-up.

CONCLUSIONS

The 33 of 77 children with DV who demonstrated a short lag time during follow-up did so,not because of a conversion to

OAB but rather once the EMG quieted in response to biofeedback, its masking effect on the already existing secondary

DO lifted, making apparent the DO that was still present particularly in those who had not been on anticholinergics. In

conclusion, in our experience children with DV and OAB do not appear to transition from one condition to the other and

thus these findings call into question the previously held notion that conversion between these two conditions does

occur in children. More symptomatic DV requires anticholinergics in addition to biofeedback.